KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLD1
All Species:
30.61
Human Site:
T495
Identified Species:
44.89
UniProt:
Q13393
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13393
NP_001123553.1
1074
124184
T495
D
D
N
E
H
R
L
T
D
V
G
S
V
K
R
Chimpanzee
Pan troglodytes
XP_526380
1125
128795
I558
A
H
H
E
K
L
V
I
I
D
Q
S
V
A
F
Rhesus Macaque
Macaca mulatta
XP_001085464
1074
124020
T495
D
D
N
E
H
R
L
T
D
V
G
S
V
K
R
Dog
Lupus familis
XP_545291
1075
123911
T495
D
D
N
E
H
R
L
T
D
V
G
S
V
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z280
1074
123950
T495
D
D
N
E
H
R
L
T
D
V
G
S
V
K
R
Rat
Rattus norvegicus
P70496
1074
123795
T495
D
D
N
E
H
R
L
T
D
V
G
S
V
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513744
295
33781
Chicken
Gallus gallus
XP_422793
1072
123414
T493
D
D
D
E
H
R
L
T
D
V
G
S
V
K
R
Frog
Xenopus laevis
NP_001129642
1039
119219
Q473
E
K
I
V
V
I
D
Q
S
V
A
F
V
G
G
Zebra Danio
Brachydanio rerio
NP_001153567
1022
117847
L455
H
V
S
S
S
V
Y
L
W
A
H
H
E
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001137610
1364
155352
T732
D
D
H
H
H
R
L
T
D
L
G
S
I
S
T
Honey Bee
Apis mellifera
XP_001121004
1135
129725
I524
D
N
N
E
H
R
L
I
D
L
G
N
T
H
Q
Nematode Worm
Caenorhab. elegans
NP_494939
1427
163517
T672
D
D
H
R
H
L
L
T
D
L
G
S
V
Q
Y
Sea Urchin
Strong. purpuratus
XP_784455
790
90080
A288
V
I
I
D
Q
R
I
A
F
I
G
G
I
D
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M9W8
1046
118792
D465
V
K
V
L
R
Y
P
D
H
L
S
S
G
I
Y
Baker's Yeast
Sacchar. cerevisiae
P36126
1683
195185
T680
G
S
F
A
P
V
R
T
N
S
F
C
K
F
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.7
97.8
91
N.A.
91
90.6
N.A.
22
79.4
75.6
66.6
N.A.
34.8
40.3
35.9
35.1
Protein Similarity:
100
92
99
95.1
N.A.
95.6
95.6
N.A.
24.8
88.8
86.3
78.3
N.A.
50.9
57.7
51
49.5
P-Site Identity:
100
20
100
100
N.A.
100
100
N.A.
0
93.3
13.3
6.6
N.A.
60
53.3
60
13.3
P-Site Similarity:
100
33.3
100
100
N.A.
100
100
N.A.
0
100
20
13.3
N.A.
80
80
80
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.6
21
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.6
35.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
0
0
0
7
0
7
7
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% C
% Asp:
57
50
7
7
0
0
7
7
57
7
0
0
0
7
0
% D
% Glu:
7
0
0
50
0
0
0
0
0
0
0
0
7
0
0
% E
% Phe:
0
0
7
0
0
0
0
0
7
0
7
7
0
7
7
% F
% Gly:
7
0
0
0
0
0
0
0
0
0
63
7
7
7
7
% G
% His:
7
7
19
7
57
0
0
0
7
0
7
7
0
7
0
% H
% Ile:
0
7
13
0
0
7
7
13
7
7
0
0
13
7
13
% I
% Lys:
0
13
0
0
7
0
0
0
0
0
0
0
7
44
0
% K
% Leu:
0
0
0
7
0
13
57
7
0
25
0
0
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
38
0
0
0
0
0
7
0
0
7
0
0
0
% N
% Pro:
0
0
0
0
7
0
7
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
7
0
0
7
0
0
7
0
0
7
7
% Q
% Arg:
0
0
0
7
7
57
7
0
0
0
0
0
0
0
38
% R
% Ser:
0
7
7
7
7
0
0
0
7
7
7
63
0
7
0
% S
% Thr:
0
0
0
0
0
0
0
57
0
0
0
0
7
0
7
% T
% Val:
13
7
7
7
7
13
7
0
0
44
0
0
57
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
7
0
0
0
0
0
0
0
13
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _